Atypical Polypoid Bladder Lesion Mimicking Urothelial Carcinoma in a Young Male: A Case Report About a Possible Autoimmune-Triggered Granulomatous Inflammation With Secondary Colonization
Severin P Hofmann, Uwe Bieri, Franz von Stauffenberg, Stefan Schneider, Gad Singer, Michael Greiner, Lukas John Hefermehl · 2025
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Description
Severin Hofmann and co-authors report the case of a twenty-eight-year-old man whose bladder growth looked like cancer but was not, in a 2025 case report. He came in with bloody urine, flank pain, and painful urination. Scans showed a thick bladder wall and narrowed kidney outlets. A scope found a large, lumpy growth of the kind bladder cancer makes. Surgeons shaved the growth out for testing.
Under the lens, the tissue held clumps of immune cells and dead zones, but no cancer. Gene sequencing found three microbes in the tissue, though their role stayed unclear. Weeks later he broke out in a rash with mouth sores, and skin tests pointed to inflamed blood vessels from an autoimmune attack. Steroid treatment cleared every symptom, the bladder growth included. The authors use the case to warn how closely inflammation can mimic cancer.
Catalog record
| CREATOR | Severin P Hofmann, Uwe Bieri, Franz von Stauffenberg, Stefan Schneider, Gad Singer, Michael Greiner, Lukas John Hefermehl |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |