Alterations in energy expenditure and muscle performance following short-term muscle immobilization and rehabilitative exercise in mice
Sunghwan Kyun, Gyuli Kwon, Deunsol Hwang, Inkwon Jang, Taeho Kim, Hun-Young Park, Sung-Woo Kim, Kiwon Lim, Jisu Kim · 2025
Read Alterations in energy expenditure and muscle performance following short-term muscle immobilization and rehabilitative exercise in mice by Sunghwan Kyun, Gyuli Kwon, Deunsol Hwang, Inkwon Jang, Taeho Kim, Hun-Young Park, Sung-Woo Kim, Kiwon Lim, Jisu Kim (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12784039.txt.
Description
Sunghwan Kyun and eight co-authors track energy expenditure and muscle performance after short term immobilization and rehabilitation exercise in mice. Immobilization rapidly wastes muscle, and its whole body metabolic effects are less clear. The study asks whether treadmill rehabilitation restores mass, function, and energy metabolism together.
Twenty male mice undergo two weeks of one sided hindlimb immobilization, then two weeks of recovery with or without treadmill exercise. Immobilization cuts body weight, lean mass, grip strength, and stride length, which confirms fast atrophy. Oddly, it also raises oxygen uptake, carbon dioxide output, fat oxidation, and energy expenditure while lowering the respiratory exchange ratio. Exercise during recovery restores lean mass, strength, and gait better than passive recovery.
Catalog record
| CREATOR | Sunghwan Kyun, Gyuli Kwon, Deunsol Hwang, Inkwon Jang, Taeho Kim, Hun-Young Park, Sung-Woo Kim, Kiwon Lim, Jisu Kim |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |