The Potential Protective Effects of EGCG Against Epilepsy‐Induced Damage in Rats by Mitigating Oxidative Stress, Inflammation, and Apoptosis

Sarah Alatawi, Manal S. Albalawi, Ruba M. Alfaifi, Rand Al-Twalhy, Manal D. Al-Johani, Danah Alanazi, Rinad M. Al-Otaibi, Hanan M. Hassan, Mohammed M. H. Al-Gayyar · 2025

Read The Potential Protective Effects of EGCG Against Epilepsy‐Induced Damage in Rats by Mitigating Oxidative Stress, Inflammation, and Apoptosis by Sarah Alatawi, Manal S. Albalawi, Ruba M. Alfaifi, Rand Al-Twalhy, Manal D. Al-Johani, Danah Alanazi, Rinad M. Al-Otaibi, Hanan M. Hassan, Mohammed M. H. Al-Gayyar (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12782337.txt.

Description

Sarah Alatawi and co-authors test a green tea compound as a shield against seizure damage in rats. Their 2025 study triggers epilepsy with a chemical convulsant, then treats with the compound at a set dose. Brain slices and gene reads track cell stress, swelling, and death signals.

Treated rats fared better in behavior, the team reports. A defense switch and its partner enzyme rose, while death and swelling signals fell. Cell stains in a memory zone looked a touch healthier as well. An enzyme tied to seizure spread also shifted. The compound's shield seems to run through boosted antioxidant defense, curbed swelling, and less cell suicide.

Catalog record

CREATORSarah Alatawi, Manal S. Albalawi, Ruba M. Alfaifi, Rand Al-Twalhy, Manal D. Al-Johani, Danah Alanazi, Rinad M. Al-Otaibi, Hanan M. Hassan, Mohammed M. H. Al-Gayyar
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12782337

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