Prognostic impact of Fusobacterium nucleatum in head and neck cancers: a meta-analysis of critical oncological outcomes

Asuman Feda Bayrak, Mehmet Emin Arayici, Ozden Savas, Erdogan Ozgur, Aydan Ozkutuk, Enis Alpin Guneri · 2025

Read Prognostic impact of Fusobacterium nucleatum in head and neck cancers: a meta-analysis of critical oncological outcomes by Asuman Feda Bayrak, Mehmet Emin Arayici, Ozden Savas, Erdogan Ozgur, Aydan Ozkutuk, Enis Alpin Guneri (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12781759.txt.

Description

Asuman Feda Bayrak and co-authors pool studies on whether a mouth bacterium worsens the outlook in head and neck cancers. The bacterium is already tied to bowel cancer's story. Its role in cancers of the mouth and throat was murkier.

Four databases were searched from the start through late 2025. Studies linking the bacterium's abundance to survival were pooled. Both overall and disease-specific survival were combined under standard models. Study quality was graded with a standard scale. If the bacterium flags worse outcomes, it could guide follow-up intensity. It might even become a target one day. The meta-analysis separates pooled signal from single-study noise.

Catalog record

CREATORAsuman Feda Bayrak, Mehmet Emin Arayici, Ozden Savas, Erdogan Ozgur, Aydan Ozkutuk, Enis Alpin Guneri
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12781759

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