Proteoglycans as Biomarkers of Medial Degeneration in Acute Stanford Type A Aortic Dissection
Ghufran Bagaber, Wenyu Song, Guangguo Fu, Kui Hu, Zhe Wang, Yubin Hu, Lai Wei, Jinmiao Chen · 2025
Read Proteoglycans as Biomarkers of Medial Degeneration in Acute Stanford Type A Aortic Dissection by Ghufran Bagaber, Wenyu Song, Guangguo Fu, Kui Hu, Zhe Wang, Yubin Hu, Lai Wei, Jinmiao Chen (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12781015.txt.
Description
Bagaber and seven co-authors review proteoglycans as blood markers for acute type A aortic dissection, in a review from twenty twenty-five. This torn-aorta emergency kills quickly and imaging is not always at hand. The standard blood marker is sensitive but poorly specific. Proteoglycans spill from the degrading middle wall layer during dissection.
Specific proteoglycans show better specificity and stability in studies. One, aggrecan, stays measurable for up to seventy-two hours. The standard marker clears within about eight hours by contrast. Late-presenting patients could still be caught by these markers. Clinical validation studies are the needed next step.
Catalog record
| CREATOR | Ghufran Bagaber, Wenyu Song, Guangguo Fu, Kui Hu, Zhe Wang, Yubin Hu, Lai Wei, Jinmiao Chen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |