Global population genomics redefines domestication and clinical diversity in the Aspergillus flavus–oryzae complex
Walter P Pfliegler, Bálint Németh, Veronika Bodnár, Tünde Pusztahelyi, Ignazio Carbone, István Pócsi · 2025
Read Global population genomics redefines domestication and clinical diversity in the Aspergillus flavus–oryzae complex by Walter P Pfliegler, Bálint Németh, Veronika Bodnár, Tünde Pusztahelyi, Ignazio Carbone, István Pócsi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12780890.txt.
Description
Walter Pfliegler and co-authors redraw the family tree of a mold, both industrial workhorse and dangerous contaminant, in a 2025 study. Aspergillus flavus poisons crops and infects people, while its domesticated cousin brews sake and soy sauce. How the two are linked, and how one was tamed, were unsettled. The team sequenced six hundred thirty-nine isolates from clinics, environments, and fermentations worldwide.
Genomes split into clear clades mixed with mosaic groups with blended ancestry. Proof points to several tamings, each on its own, that gave rise to the food strain. Those from clinics scattered across clades, some in the same groups as food strains. This hints that taming itself shaped pathogen diversity. The authors say species lines need new thought. The work informs food safety, biocontrol, and surveillance of a fungus that feeds and threatens us.
Catalog record
| CREATOR | Walter P Pfliegler, Bálint Németh, Veronika Bodnár, Tünde Pusztahelyi, Ignazio Carbone, István Pócsi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |