Landscape targeted of therapy in advanced pancreatic adenocarcinoma: a network meta-analysis of randomized controlled trials [2010–2024]
Huixin Ma, Sheng Wang, Yunjin Ya, Yun Jin, Shikang Deng · 2025
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Description
Huixin Ma and co-authors rank targeted drug mixes for advanced pancreatic cancer, in a 2025 review. This cancer offers few good options once it spreads. A standard drug forms the base of most care, often joined with newer targeted agents, yet no one had ranked the mixes head to head.
The team pooled thirteen trials with more than four thousand patients, run between 2010 and 2024. Most mixes failed to beat the base drug alone on survival. One agent that blocks a growth signal did help in set subgroups. The authors chart the whole field, which can steer doctors and trial designers toward the most hopeful paths.
Catalog record
| CREATOR | Huixin Ma, Sheng Wang, Yunjin Ya, Yun Jin, Shikang Deng |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |