Association of perioperative cholesterol depletion with anastomotic leak after esophagectomy for cancer: a retrospective study

Mingrui Liu, Simian He, Enwei Zhou, Binhui Ren · 2025

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Description

Mingrui Liu and co-authors link a drop in cholesterol around surgery to leaks after food pipe cancer surgery in a 2025 study. A leak at the surgical join is one of the worst problems after this operation. Poor nutrition raises risk, and nutrition scores also reflect stress and swelling in the body, so the team tested three such scores.

Records for more than seventeen hundred patients over four years were reviewed, and about one in twelve developed a leak. Changes in two nutrition scores did not differ between leak and non leak groups. Change in the third score did differ, and among its parts only cholesterol change stood out. The authors discuss cholesterol loss as a warning sign.

Catalog record

CREATORMingrui Liu, Simian He, Enwei Zhou, Binhui Ren
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12780416

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