Hemodynamic mechanisms in patients with atrial functional and structural mitral regurgitation based on 4D flow cardiac MRI

Munehide Nagao, Keiichi Itatani, Toshihiko Shibata, Akimasa Morisaki, Kenta Nishiya, Goki Inno, Takumi Kawase, Yukihiro Nishimoto, Kazuki Noda, Ryo Nangoya, Yosuke Takahashi · 2025

Read Hemodynamic mechanisms in patients with atrial functional and structural mitral regurgitation based on 4D flow cardiac MRI by Munehide Nagao, Keiichi Itatani, Toshihiko Shibata, Akimasa Morisaki, Kenta Nishiya, Goki Inno, Takumi Kawase, Yukihiro Nishimoto, Kazuki Noda, Ryo Nangoya, Yosuke Takahashi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12780406.txt.

Description

Munehide Nagao and co-authors use moving MRI scans of blood flow to compare two kinds of leaky heart valve. In one kind the valve itself is sound but the chamber above it has stretched, pulling the valve open; lasting irregular heartbeat is the usual cause. In the other, part of the valve physically sags. The team scanned ten surgical patients of each kind before their operations.

The stretched-chamber group pumped notably less blood per minute and lost less flow energy on the body's side of the heart, but more on the lung side, than the sagging-valve group. The authors argue these flow patterns explain how the two conditions burden the heart differently and may guide treatment choices.

Catalog record

CREATORMunehide Nagao, Keiichi Itatani, Toshihiko Shibata, Akimasa Morisaki, Kenta Nishiya, Goki Inno, Takumi Kawase, Yukihiro Nishimoto, Kazuki Noda, Ryo Nangoya, Yosuke Takahashi
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12780406

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