Bronchoscopic ablation for non-small cell lung cancer
Kanishka Rangamuwa, Daniel Steinfort · 2025
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Description
Kanishka Rangamuwa and Daniel Steinfort review a new way to attack lung tumors: ablation delivered through a bronchoscope, working from inside the airways rather than through the chest wall. They survey four techniques in early clinical use, burning with radio waves or microwaves, zapping with pulsed electric fields, and freezing.
The scope-based methods hit their targets with good safety records and fewer complications than needle-through-skin approaches, though rare deaths in the heat-based trials demand care. The electric field method spares nearby structures and may wake up the immune system, and freezing proved feasible in small groups. A theme across all four is possible immune stimulation that could partner with immunotherapy. The authors stress the evidence is young: small studies, short follow-up, mixed endpoints. Bigger trials must settle durability and the best technique.
Catalog record
| CREATOR | Kanishka Rangamuwa, Daniel Steinfort |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |