Inhalation & intravenous: umbilical cord mesenchymal stem cell-derived exosomes therapy strategy for acute respiratory distress syndrome in a murine model
Luyu Yang, Zhimin Cao, Yuanfang Xing, Yuanming Pan, Can Yang, Li Zhang, Hong Zhao, Teng Ma, Huan Ye · 2025
Read Inhalation & intravenous: umbilical cord mesenchymal stem cell-derived exosomes therapy strategy for acute respiratory distress syndrome in a murine model by Luyu Yang, Zhimin Cao, Yuanfang Xing, Yuanming Pan, Can Yang, Li Zhang, Hong Zhao, Teng Ma, Huan Ye (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12780377.txt.
Description
Luyu Yang and co-authors published this animal study in 2025. It tests a possible treatment for acute respiratory distress syndrome, a severe lung failure that became far more common during the COVID-19 pandemic. The treatment uses exosomes, tiny parcels released by stem cells taken from umbilical cord tissue.
The team gave the treatment to mice with lung injury in three ways: breathed in, injected into a vein, or both routes together. Mice that got both routes breathed better and had lower levels of two inflammation signals in the blood. The combined route also cut the death of lung cells that line the air sacs. The authors say giving the treatment both ways worked best.
Catalog record
| CREATOR | Luyu Yang, Zhimin Cao, Yuanfang Xing, Yuanming Pan, Can Yang, Li Zhang, Hong Zhao, Teng Ma, Huan Ye |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |