Immunohistochemical study of Rho-kinase pathway expression in a mouse model of prostate hypertrophy for preliminary study of progressive prostate cancer model establishment
Young-Min Yang, Koichi Kitagawa, Yuto Hirata, Michika Moriwaki, Tenei Ono, Yi-Te Chiang, Kuan-Chou Chen, Katsumi Shigemura · 2025
Read Immunohistochemical study of Rho-kinase pathway expression in a mouse model of prostate hypertrophy for preliminary study of progressive prostate cancer model establishment by Young-Min Yang, Koichi Kitagawa, Yuto Hirata, Michika Moriwaki, Tenei Ono, Yi-Te Chiang, Kuan-Chou Chen, Katsumi Shigemura (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12779437.txt.
Description
Young-Min Yang and co-authors report a mouse study from 2025 that sets up later prostate cancer work. The team first needs a good animal model of an enlarged prostate. They gave a hormone to castrated mice to grow the prostate, then checked tissues in the prostate and bladder. Stained tissue slices let them track key marker proteins.
Mice that got the hormone had heavier prostates than the control groups. Their prostate tissue showed more of one receptor marker linked to growth signals. Bladder tissue showed more of two other markers, one tied to muscle tightening pathways. The work is an early step toward a model for testing how prostate disease grows and spreads.
Catalog record
| CREATOR | Young-Min Yang, Koichi Kitagawa, Yuto Hirata, Michika Moriwaki, Tenei Ono, Yi-Te Chiang, Kuan-Chou Chen, Katsumi Shigemura |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |