The influence of CXCL9 on M2 macrophages in lung cancer development
Lin Mi, Liyun Xu, Zhijun Chen, Yeye Zheng · 2025
Read The influence of CXCL9 on M2 macrophages in lung cancer development by Lin Mi, Liyun Xu, Zhijun Chen, Yeye Zheng (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12776223.txt.
Description
Lin Mi and co-authors study a chemical messenger that reins in tumor-helping macrophages in lung cancer, in a 2025 paper. Macrophages in tumors often take an M2 form that feeds growth and spread. The messenger CXCL9 has been flagged as a brake on that form.
In dish work, M2 macrophages boosted lung cancer cell growth, movement, and invasion. Adding CXCL9 blunted all three boosts and curbed the M2 shift itself. Protein and gene reads tracked how the messenger rewired the cells. Patient sample checks and prognosis data framed the lab results. The study positions CXCL9 as a lever on the tumor's support crew, a route that attacks cancer's helpers rather than the cancer alone.
Catalog record
| CREATOR | Lin Mi, Liyun Xu, Zhijun Chen, Yeye Zheng |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |