Sarcopenia-driven gene model as a clinically actionable prognostic signature for head and neck squamous cell carcinoma
Kun Gao, Zheran Liu, Meng Dou, Ge Song, Jiacheng Li, Ping Ai, Jiagang He, Jitao Zhou · 2025
Read Sarcopenia-driven gene model as a clinically actionable prognostic signature for head and neck squamous cell carcinoma by Kun Gao, Zheran Liu, Meng Dou, Ge Song, Jiacheng Li, Ping Ai, Jiagang He, Jitao Zhou (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12776216.txt.
Description
Kun Gao and co-authors build in 2025 a gene risk model tied to muscle loss for head and neck cancer outlook. Muscle loss can cut treatment tolerance and raise side effects, which worsens survival. Its link to outcomes in this cancer type was not well mapped.
Scans and gene data from more than one hundred sixty patients anchor the study. Muscle area at a neck bone level marks the loss state for each patient. Gene, immune, and cell data splits between loss groups feed a risk score built by a shrink method. An outside gene database checks the score. The aim is a tool clinics can act on when planning care.
Catalog record
| CREATOR | Kun Gao, Zheran Liu, Meng Dou, Ge Song, Jiacheng Li, Ping Ai, Jiagang He, Jitao Zhou |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |