Clinical characteristics of post-operative N2 nodal upstaging in non-small cell lung cancer: a retrospective cohort study

Sun Young Choi, Myung Jin Song, Byung Soo Kwon, Yeon Wook Kim, Jong Sun Park, Sukki Cho, Jae Ho Lee, Choon-Taek Lee, Sung Yoon Lim · 2025

Read Clinical characteristics of post-operative N2 nodal upstaging in non-small cell lung cancer: a retrospective cohort study by Sun Young Choi, Myung Jin Song, Byung Soo Kwon, Yeon Wook Kim, Jong Sun Park, Sukki Cho, Jae Ho Lee, Choon-Taek Lee, Sung Yoon Lim (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12775689.txt.

Description

Sun Choi and co-authors ask whether surprise node spread found after lung cancer surgery hurts survival as much as known spread. Their 2025 study reviews 177 patients whose removed tissue confirmed N2 nodal disease. Scans and needle sampling staged them before the operation.

Over half the group, about fifty-three percent, were upstaged only after surgery. The surprise nodes cluster under the carina and near the aorta, and two in five measure under five millimeters. Five-year survival matches the known-spread group. Freedom from progression actually runs better in the upstaged group. The authors suggest small hidden nodes behave less aggressively than bulky known disease, easing fears that missed staging alone dooms these patients.

Catalog record

CREATORSun Young Choi, Myung Jin Song, Byung Soo Kwon, Yeon Wook Kim, Jong Sun Park, Sukki Cho, Jae Ho Lee, Choon-Taek Lee, Sung Yoon Lim
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12775689

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