Pseudoarthrosis after thoracolumbar fusion in patients with Parkinson’s disease
Matthew Lindsey, Hannah Levy, Tyler Allen, Andrew Pumford, Abdelrahman Hamouda, Brian Kelley, Steven Girdler, Anthony Mikula, Brian Goh, Brett Freedman, Arjun Sebastian, Ahmad Nassr · 2025
Read Pseudoarthrosis after thoracolumbar fusion in patients with Parkinson’s disease by Matthew Lindsey, Hannah Levy, Tyler Allen, Andrew Pumford, Abdelrahman Hamouda, Brian Kelley, Steven Girdler, Anthony Mikula, Brian Goh, Brett Freedman, Arjun Sebastian, Ahmad Nassr (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12775613.txt.
Description
Matthew Lindsey and co-authors present a 2025 journal article on failed spinal fusion in patients with Parkinson's disease. Failed fusion, called pseudoarthrosis, is the top reason for repeat spine surgery, and Parkinson's brings posture problems that strain fusions. The team reviewed adults with the disease who had thoracolumbar fusion at one center from 2017 to 2022.
Of 59 patients, about 27 percent failed to fuse. Failure tracked with screw loosening and with higher death rates at ninety days and one year. Tremor, low bone density scores, wheelchair use, and trauma as the surgery reason all raised the risk. Disease duration and drug use showed no link.
Catalog record
| CREATOR | Matthew Lindsey, Hannah Levy, Tyler Allen, Andrew Pumford, Abdelrahman Hamouda, Brian Kelley, Steven Girdler, Anthony Mikula, Brian Goh, Brett Freedman, Arjun Sebastian, Ahmad Nassr |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |