Nanoarchaeosomes for synergistic photochemotherapy in triple-negative breast cancer

Shaik Sameer Basha, Sachin Thomas, Subastri Ariraman, Renugaa Suresh Babu, Poornima Budime Santhosh, Lyubomir Stoychev, Julia Genova, Albena Daskalova, Bhagyashree Bhoir, Vimalraj Selvaraj, Swathi Sudhakar · 2025

Read Nanoarchaeosomes for synergistic photochemotherapy in triple-negative breast cancer by Shaik Sameer Basha, Sachin Thomas, Subastri Ariraman, Renugaa Suresh Babu, Poornima Budime Santhosh, Lyubomir Stoychev, Julia Genova, Albena Daskalova, Bhagyashree Bhoir, Vimalraj Selvaraj, Swathi Sudhakar (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12775512.txt.

Description

Shaik Sameer Basha and ten co-authors build a tiny delivery system that pairs heat and drugs against triple-negative breast cancer. This cancer lacks the hooks that many targeted drugs use, and standard care can harm the whole body. Their 2025 design uses shells made from archaeal lipids, which stay stable in the body. The shells carry cisplatin, a cancer drug, plus gold rods that heat up under near-infrared light.

The lipid shells load a lot of drug and hold together well. When light hits the rods, heat and drug attack the tumor together. The authors present the platform as a way to focus treatment on the tumor and spare other tissue. It joins a push for combined therapies against cancers with few good options.

Catalog record

CREATORShaik Sameer Basha, Sachin Thomas, Subastri Ariraman, Renugaa Suresh Babu, Poornima Budime Santhosh, Lyubomir Stoychev, Julia Genova, Albena Daskalova, Bhagyashree Bhoir, Vimalraj Selvaraj, Swathi Sudhakar
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE72 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12775512

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