Sepsis-induced coagulopathy: recent insights on the role and clinical application of neutrophil extracellular trap formation
Shams ElDoha Galal ElDin Zaiema, Nahela Ahmed Shalaby, Toka Hassaan Mohamed, Aya Ali Mahmoud Bayoumy, Raghda El Sayed Abdel Monem Galal · 2025
Read Sepsis-induced coagulopathy: recent insights on the role and clinical application of neutrophil extracellular trap formation by Shams ElDoha Galal ElDin Zaiema, Nahela Ahmed Shalaby, Toka Hassaan Mohamed, Aya Ali Mahmoud Bayoumy, Raghda El Sayed Abdel Monem Galal (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12775430.txt.
Description
Zaiema and co-authors test whether markers of neutrophil traps can judge sepsis and its clotting problems. In sepsis, the immune response to infection harms organs and can trigger widespread clotting. Neutrophils cast out web-like traps that aid this harmful clotting.
The case-control study followed 138 sepsis patients for seven days, plus 80 healthy controls. It tracked who developed the clotting disorder and who died. Histone levels tied closely to early inflammation and to clotting problems. Another marker, myeloperoxidase, predicted short-term death no matter the clotting status. Rising levels of both marked higher risk.
Catalog record
| CREATOR | Shams ElDoha Galal ElDin Zaiema, Nahela Ahmed Shalaby, Toka Hassaan Mohamed, Aya Ali Mahmoud Bayoumy, Raghda El Sayed Abdel Monem Galal |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |