Tolerability and effect of inhibiting microfibrillar-associated protein 4 in small intestinal anastomotic healing

Rasmus Refshauge Andresen, Jesper Brandt Pedersen, Paula Frederikke Hellsegg Grünfeld, Charlotte Skoie Nielsen, Anna Lings Kjelgaard, Anders Frederik Højer Kolind, Nils Grimm, Kasper Emil Rosenbech, Henriette Kirkeby Høiberg, Johanne Kalland, Mie Dilling, Gunvor Iben Madsen, Anders Schlosser, Lasse · 2025

Read Tolerability and effect of inhibiting microfibrillar-associated protein 4 in small intestinal anastomotic healing by Rasmus Refshauge Andresen, Jesper Brandt Pedersen, Paula Frederikke Hellsegg Grünfeld, Charlotte Skoie Nielsen, Anna Lings Kjelgaard, Anders Frederik Højer Kolind, Nils Grimm, Kasper Emil Rosenbech, Henriette Kirkeby Høiberg, Johanne Kalland, Mie Dilling, Gunvor Iben Madsen, Anders Schlosser, Lasse (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12775135.txt.

Description

Andresen and a large team tested in twenty twenty-five a drug that blocks a scar protein, to aid heal of gut joins in pigs. Crohn's ill oft leaves gut scars that narrow the tube and need cuts. The blocked protein helps scar build in many tissues.

They made two joins in each of forty-five pigs and shot each join with the drug, a known aid, or a plain fluid. The drug was well borne at both doses over up to four weeks. Scar at the join fell by near a fourth with the drug. Muscle cells shifted from a scar form to a work form in drug joins.

Catalog record

CREATORRasmus Refshauge Andresen, Jesper Brandt Pedersen, Paula Frederikke Hellsegg Grünfeld, Charlotte Skoie Nielsen, Anna Lings Kjelgaard, Anders Frederik Højer Kolind, Nils Grimm, Kasper Emil Rosenbech, Henriette Kirkeby Høiberg, Johanne Kalland, Mie Dilling, Gunvor Iben Madsen, Anders Schlosser, Lasse
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE59 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12775135

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