Inhaled salbutamol delivery in small children with disposable and reusable spacers: an in vitro study
Laura Ojanperä, Lauri Lehtimäki, Balázs Kelemen, Peter Csonka · 2025
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Description
Laura Ojanpera and co-authors compare, in twenty twenty-five, spacer devices that help small children inhale asthma medicine. A spacer is a chamber between an inhaler and the child's mouth. It holds the spray so the child can breathe it in slowly. Disposable paper spacers may suit some clinic uses, but data were scarce. The team tested two disposable spacers against three reusable chambers in the lab, using a child throat model.
They used three child breathing patterns, calm and blocked. One reusable chamber gave the highest fine dose that can reach the lungs. Blocked breathing raised throat deposits for all spacers. Reusable chambers beat disposable ones overall. Of the disposable pair, the valved one did better.
Catalog record
| CREATOR | Laura Ojanperä, Lauri Lehtimäki, Balázs Kelemen, Peter Csonka |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |