The role of TGF-β1 C-509T and TGF-β1 T869C polymorphisms in susceptibility to tuberculosis infection in a Sudanese population: a case-control study
Salma A. Moharrum, Naser Eldin Bilal, Najwa A. Mhmoud · 2025
Read The role of TGF-β1 C-509T and TGF-β1 T869C polymorphisms in susceptibility to tuberculosis infection in a Sudanese population: a case-control study by Salma A. Moharrum, Naser Eldin Bilal, Najwa A. Mhmoud (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12771907.txt.
Description
Genes that tune immune signals may shape who catches tuberculosis. Salma Moharrum, Naser Eldin Bilal, and Najwa Mhmoud tested two variants of one such gene in Sudan in 2025, the first study of its kind there. They compared two hundred newly diagnosed lung tuberculosis patients at a Khartoum hospital with two hundred healthy controls.
One variant stood out: people carrying the changed form at one position had nearly three times the risk of developing the disease. The second variant showed no clear difference between patients and controls. The authors say even one copy of the risky form matters in this population. They note the work grew from a doctoral thesis and adds Sudanese data to a field built on other populations.
Catalog record
| CREATOR | Salma A. Moharrum, Naser Eldin Bilal, Najwa A. Mhmoud |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |