Salivary metabolites for pancreatic cancer diagnosis: a systematic review and meta-analysis
Maryam Koopaie, Mahnaz Fatahzadeh, Sajad Kolahdooz · 2025
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Description
Maryam Koopaie, Mahnaz Fatahzadeh, and Sajad Kolahdooz combined studies on using saliva chemicals to diagnose pancreatic cancer. The cancer is usually found late and current tests can be invasive or inaccurate early on. Saliva is easy to collect and carries many small molecules that might betray disease. Writing in twenty twenty-five, the team searched many databases without language limits and kept the few diagnostic studies that met their rules. Quality was rated with a standard tool, and results were pooled across thousands of patients and controls.
Pooled accuracy was moderate to good, with sensitivity and specificity each near four fifths and an overall ranking score in a useful range. Panels that combined several saliva chemicals beat single markers by a clear margin. The authors present saliva testing as a promising, painless aid, while the small number of studies argues for larger confirmatory work.
Catalog record
| CREATOR | Maryam Koopaie, Mahnaz Fatahzadeh, Sajad Kolahdooz |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |