Combination use of intravenous ketamine-midazolam as a sedative agent in endoscopic retrograde cholangiopancreatography: a randomized control trial

Rajdave Singh Sadu Singh, Azlanudin Azman, Jegan Thanabalan, Chik Ian, Boo Han Sin, Razman Jarmin, Fahrol Fahmy Jaafar · 2025

Read Combination use of intravenous ketamine-midazolam as a sedative agent in endoscopic retrograde cholangiopancreatography: a randomized control trial by Rajdave Singh Sadu Singh, Azlanudin Azman, Jegan Thanabalan, Chik Ian, Boo Han Sin, Razman Jarmin, Fahrol Fahmy Jaafar (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12769659.txt.

Description

Rajdave Singh Sadu Singh and co-authors run a trial of two drug mixes for deep sedation in a 2025 paper. The setting is a scope test of the bile and pancreas ducts, which needs deep sedation. The standard drug is costly and needs a trained sedation doctor.

Eighty-five patients were split by chance into two groups. One mix paired ketamine with midazolam, the other paired midazolam with pethidine. The first mix gave deeper sedation at each stage of the test. Patients and scope doctors also scored it higher. The trial suggests a cheaper mix can work well where the standard drug is hard to use.

Catalog record

CREATORRajdave Singh Sadu Singh, Azlanudin Azman, Jegan Thanabalan, Chik Ian, Boo Han Sin, Razman Jarmin, Fahrol Fahmy Jaafar
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12769659

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