Deacetylasperulosidic Acid Methyl Ester Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis by Suppressing Inflammation and Modulating Gut Microbiota
Li Chen, Chunyan Chen, Qixiang Chen, Ting Jiang, Lingli Zheng, Rong Tang, Cheng Wang · 2025
Read Deacetylasperulosidic Acid Methyl Ester Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis by Suppressing Inflammation and Modulating Gut Microbiota by Li Chen, Chunyan Chen, Qixiang Chen, Ting Jiang, Lingli Zheng, Rong Tang, Cheng Wang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12769619.txt.
Description
Li Chen and six co-authors tested a plant compound against liver scarring in mice in a 2025 study. Scarring builds when a hurt liver heals too much, and it can end in organ failure or cancer. No good drug yet stops it. The compound they used comes from plants in the madder family and is known to calm swelling.
Mice given a toxin that scars the liver got the compound as a treatment. Their liver damage, blood markers, and scar tissue all dropped next to untreated mice. Swelling signals in the liver fell too. The gut wall held up better, with tighter seals between cells, and the gut microbe mix shifted in ways the authors link to the gain.
Catalog record
| CREATOR | Li Chen, Chunyan Chen, Qixiang Chen, Ting Jiang, Lingli Zheng, Rong Tang, Cheng Wang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |