PP40 Enoxaparin: Synthesis of Evidence for Expanding the Current National Clinical Protocol and Therapeutic Guidelines

Gleidson Cardoso Spinola, Bárbara de Castro dos Santos Silva, Carolina Santos Silva, Manuela Fernandes de Almeida Mello, Rouseli Gonçalves de Menezes · 2025

Read PP40 Enoxaparin: Synthesis of Evidence for Expanding the Current National Clinical Protocol and Therapeutic Guidelines by Gleidson Cardoso Spinola, Bárbara de Castro dos Santos Silva, Carolina Santos Silva, Manuela Fernandes de Almeida Mello, Rouseli Gonçalves de Menezes (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12768800.txt.

Description

Gleidson Spinola and four colleagues present a 2025 evidence review supporting wider use of enoxaparin, a blood-thinning injection, for pregnant women at risk of dangerous clots. Brazil's national treatment guidelines currently limit its use; the team checked whether the evidence justifies expanding them, weighing benefits, harms, and costs.

Eight systematic reviews met their criteria. The drug cut clotting events and miscarriages and raised live births, but raised bleeding risk and allergic reactions. Treating pregnant women in Bahia state could avoid about two hundred forty thousand dollars a year in hospital costs. The first-year budget impact came to near one hundred sixty-three thousand dollars. A state expert group now drafts an expanded protocol.

Catalog record

CREATORGleidson Cardoso Spinola, Bárbara de Castro dos Santos Silva, Carolina Santos Silva, Manuela Fernandes de Almeida Mello, Rouseli Gonçalves de Menezes
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12768800

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