Development and validation of an AI-based lung lobe auto-contouring tool using radiation therapy planning free-breathing images

Peter Ciaccio, Joseph Lombardo, Andrew Fuquay, Soroush Pahlavian, Rachel Grimm, Jun Kang, Wookjin Choi, Paul Sullivan, Yevgeniy Vinogradskiy · 2025

Read Development and validation of an AI-based lung lobe auto-contouring tool using radiation therapy planning free-breathing images by Peter Ciaccio, Joseph Lombardo, Andrew Fuquay, Soroush Pahlavian, Rachel Grimm, Jun Kang, Wookjin Choi, Paul Sullivan, Yevgeniy Vinogradskiy (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12768033.txt.

Description

Peter Ciaccio and co-authors build and validate an AI tool that outlines lung lobes on planning scans in a 2025 paper. Radiation dose judged lobe by lobe predicts lung toxicity better, but hand-drawing five lobes is slow and hard. Automation could make lobar dosimetry routine.

A clinician contoured the lobes of fifty patients from two centers on free-breathing scans. A residual 3D network trained on forty cases and was checked against expert outlines on the rest. Accuracy results fill the paper. If auto-contours prove trustworthy, planners gain finer toxicity forecasts without hours of manual tracing per patient.

Catalog record

CREATORPeter Ciaccio, Joseph Lombardo, Andrew Fuquay, Soroush Pahlavian, Rachel Grimm, Jun Kang, Wookjin Choi, Paul Sullivan, Yevgeniy Vinogradskiy
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE15 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12768033

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