Single‐Cell Transcriptomics Reveal Microenvironment Alterations in Canine Peri‐Implantitis
Ming Wang, Dong Zhang, Chunhui Liao, Daner Wu, Ningbo Geng, Yixin Xia, Yu Chen, Songling Chen, Wei Peng, Jasbir Arora (RSS) · 2025
Read Single‐Cell Transcriptomics Reveal Microenvironment Alterations in Canine Peri‐Implantitis by Ming Wang, Dong Zhang, Chunhui Liao, Daner Wu, Ningbo Geng, Yixin Xia, Yu Chen, Songling Chen, Wei Peng, Jasbir Arora (RSS) (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12767392.txt.
Description
Ming Wang and co-authors map, cell by cell, the tissue damage around failing dental implants. Their 2025 study builds the disease in beagle dogs so healthy tissue can be sampled fairly. Past work lumped gum and bone together, hiding how each site changes on its own.
Single-cell gene reads showed swollen ranks of inflammation-linked cells in both gum and bone. The gum grew vessel and fibre cells that call in immune fighters. Bone grew a fibre cell type that talks to immune cells through a complement signal. The authors offer the atlas as a source of drug targets. The dog model is defended as a fair stand-in.
Catalog record
| CREATOR | Ming Wang, Dong Zhang, Chunhui Liao, Daner Wu, Ningbo Geng, Yixin Xia, Yu Chen, Songling Chen, Wei Peng, Jasbir Arora (RSS) |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |