Prevalence and incidence of amyloid transthyretin amyloidosis in the USA: insights from claims databases and electronic health records
Pedro A Laires, Xiaolei Li, Aishwarya M Uday, Candida Cristina Quarta, Ana Martins Silva · 2025
Read Prevalence and incidence of amyloid transthyretin amyloidosis in the USA: insights from claims databases and electronic health records by Pedro A Laires, Xiaolei Li, Aishwarya M Uday, Candida Cristina Quarta, Ana Martins Silva (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12766817.txt.
Description
Pedro Laires and co-authors estimate how common a rare disease is in the USA in a 2025 paper. The disease, ATTR amyloidosis, harms the heart, the nerves, or both. Hard coding in records makes counts tricky, so the team used claims and health record data.
They drew on a large data store covering 2016 to 2023 and built narrow and broad case definitions. For 2022, the narrow estimate put new cases at about 17 per million people. Existing cases came to about 60 per million. Rates rose from 2019 to 2022, driven by the heart form. The study gives up-to-date counts by disease type.
Catalog record
| CREATOR | Pedro A Laires, Xiaolei Li, Aishwarya M Uday, Candida Cristina Quarta, Ana Martins Silva |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |