CORE-ALI: protocol for a pan-European mixed-methods study to develop a core outcome set for acute lower limb ischaemia

Maram Darwish, Lewis Meecham, Leszek Kukulski, Sabrina L M Zwetsloot, Mario D’Oria, Laura Schönherr, Petar Zlatanovic, Vincent Jongkind, Robert Hinchliffe, Florian K Enzmann, Alexander Croo · 2025

Read CORE-ALI: protocol for a pan-European mixed-methods study to develop a core outcome set for acute lower limb ischaemia by Maram Darwish, Lewis Meecham, Leszek Kukulski, Sabrina L M Zwetsloot, Mario D’Oria, Laura Schönherr, Petar Zlatanovic, Vincent Jongkind, Robert Hinchliffe, Florian K Enzmann, Alexander Croo (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12766812.txt.

Description

Maram Darwish and co-authors set out a plan to fix outcome chaos in leg ischemia care in a 2025 protocol. Acute lower limb ischemia is a limb and life emergency, yet trials report its outcomes in clashing ways that block shared lessons. The CORE-ALI study aims to build one core outcome set for Europe.

Phase one hears patients, clinicians, and policymakers in interviews to draft a candidate list. A Delphi vote over rounds then trims it by consent. A final meeting locks the set. Multilingual steps and safe data rules run through the design.

Catalog record

CREATORMaram Darwish, Lewis Meecham, Leszek Kukulski, Sabrina L M Zwetsloot, Mario D’Oria, Laura Schönherr, Petar Zlatanovic, Vincent Jongkind, Robert Hinchliffe, Florian K Enzmann, Alexander Croo
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12766812

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