Changes in myocardial blood flow and microvascular resistance in patients with coronary artery disease undergoing transcatheter aortic valve implantation
Eron Yones, Rebecca Gosling, Daniel Taylor, Tom Alexander Howard Newman, Mark Sammut, Saadia Aslam, Javaid Iqbal, Muhammad Aetesam-ur-Rahman, Kenneth Morgan, Amir Aziz, Melanie Neville, Ever Grech, Paul D Morris, Julian Gunn · 2025
Read Changes in myocardial blood flow and microvascular resistance in patients with coronary artery disease undergoing transcatheter aortic valve implantation by Eron Yones, Rebecca Gosling, Daniel Taylor, Tom Alexander Howard Newman, Mark Sammut, Saadia Aslam, Javaid Iqbal, Muhammad Aetesam-ur-Rahman, Kenneth Morgan, Amir Aziz, Melanie Neville, Ever Grech, Paul D Morris, Julian Gunn (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12766762.txt.
Description
Eron Yones and thirteen colleagues measure how replacing a narrowed aortic valve changes blood flow in the heart muscle of patients who also have coronary disease. Seven patients had detailed checks of body function before valve replacement and six months after. The checks combined angiography, magnetic resonance imaging, and computer flow modeling.
Coronary flow reserve improved a lot after the procedure. The driver was a large drop in resting blood flow, about a third. Resistance in the small vessels did not change; it stayed flat. Heart muscle mass also shrank. The authors read the pattern as the relieved heart demanding less blood at rest and remodeling. The small vessels themselves, they say, did not change.
Catalog record
| CREATOR | Eron Yones, Rebecca Gosling, Daniel Taylor, Tom Alexander Howard Newman, Mark Sammut, Saadia Aslam, Javaid Iqbal, Muhammad Aetesam-ur-Rahman, Kenneth Morgan, Amir Aziz, Melanie Neville, Ever Grech, Paul D Morris, Julian Gunn |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |