Metal-Based Nanomedicines for Inducing Programmed Cell Death to Enhance the Efficacy of Cancer Immunotherapy
Xiaoliang Cheng, Nayoon Park, Yonghyun Lee · 2025
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Description
Xiaoliang Cheng, Nayoon Park, and Yonghyun Lee present a 2025 review of metal-based nanomedicines for cancer. Metal ions such as iron, copper, calcium, zinc, and manganese keep cells in balance, and pushing them out of balance can trigger programmed cell death. Tumors are a tempting target for that trick.
The review explains how each metal kills cells and stirs the immune system, then surveys nanoparticles built to deliver metal ions into tumors or made of metal themselves. Early results suggest these particles can make immunotherapy work harder by turning quiet tumors into visible targets. The authors close with the hard problems of making such drugs at scale and proving them safe enough for the clinic.
Catalog record
| CREATOR | Xiaoliang Cheng, Nayoon Park, Yonghyun Lee |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 96 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |