Dupilumab-Induced Systemic Hypoperfusion in an Elderly Patient: A Case Report
Huishang Feng, Yao Liu, Xinglu Dong, Li Zhou · 2025
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Description
Huishang Feng and co-authors report a drug side effect case in a 2025 paper. Dupilumab is widely used for a blistering skin disease of the elderly and is held to be safe. A 96 year old man with that disease, plus diabetes and a past stroke, tells a different story.
Within a day to three days of each shot, his blood pressure fell, his awareness dulled, and he ate less. Scans showed strokes in the border zones between brain arteries, the pattern of low flow. On one visit, fluids given ahead of the shot prevented new damage. On another, without fluids, a mini stroke followed. The case flags flow failure as a risk to watch.
Catalog record
| CREATOR | Huishang Feng, Yao Liu, Xinglu Dong, Li Zhou |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |