A Complex Case of Hemophagocytic Lymphohistiocytosis Secondary to Untreated Hepatitis C: Diagnostic Challenges
Zachrieh Alhaj, Alexander Konopnicki, Zaid Almubaid, Khushali Roy, Thomas Le, Paul S. Park · 2025
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Description
Zachrieh Alhaj and co-authors report a tangled case from 2025 of a severe immune overreaction in a sixty-one-year-old man. The condition drives immune cells to attack the body, causing storm-like fever and organ harm. It is often set off by cancer, immune disease, or infection. This man had long-untreated hepatitis C and came in with signs of severe sepsis, yet most infection tests came back clear.
Other tests hinted at a fungal cause and at a rare germ, and broad drugs did not stop his fevers. He met five of the eight set marks for the condition, and targeted treatment ended the fevers at once. Deeper blood tests cleared the two hinted germs, so the team laid the cause on his untreated hepatitis C. The case shows how hard the trigger can be to pin down, and how much early treatment matters.
Catalog record
| CREATOR | Zachrieh Alhaj, Alexander Konopnicki, Zaid Almubaid, Khushali Roy, Thomas Le, Paul S. Park |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 15 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |