Colloidal Chemistry and Nanostructure Engineering of Gold Nanorods for Glioblastoma Applications

Sofia-Maria Gratsia, Ioannis Maris, Evangelia Tsitsou, Elias Sakellis, Nikos Boukos, Eleni K. Efthimiadou · 2025

Read Colloidal Chemistry and Nanostructure Engineering of Gold Nanorods for Glioblastoma Applications by Sofia-Maria Gratsia, Ioannis Maris, Evangelia Tsitsou, Elias Sakellis, Nikos Boukos, Eleni K. Efthimiadou (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12756834.txt.

Description

Sofia-Maria Gratsia and five co-authors engineer gold nanorods to treat glioblastoma. Glioblastoma is hard to treat in part because drugs struggle to reach the tumor and spare healthy tissue. Gold nanorods with precise size and shape can be tuned for uptake by tumor cells and for crossing barriers.

Controlled synthesis yields rods that are checked by light scattering and electron microscopy. Harm tests compare a glioblastoma cell line with a normal skin cell line. The tests check which line the rods harm more and how safe they look. Fluorescence imaging and flow cytometry show strong uptake into cells by endocytosis. The authors present the rods as a promising platform at nano scale for targeted therapy and precise care in this cancer.

Catalog record

CREATORSofia-Maria Gratsia, Ioannis Maris, Evangelia Tsitsou, Elias Sakellis, Nikos Boukos, Eleni K. Efthimiadou
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12756834

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