Biospectroscopy Combined with Multivariate Analysis as Tools for Identifying Trypanosoma cruzi Discrete Typing Units in Triatoma brasiliensis (Hemiptera: Reduviidae: Triatominae)
Jéssica T. Jales, Lavínia H. S. Pereira, Leomir A. S. de Lima, Raniery de O. Santana, Anne B. F. Câmara, Pedro Ramon da S. Aquino, Paulo Marcos M. Guedes, Andressa Noronha Barbosa-Silva Carvalho, Kássio M. G. Lima, Renata A. Gama, Antonia C. J. Câmara · 2025
Read Biospectroscopy Combined with Multivariate Analysis as Tools for Identifying Trypanosoma cruzi Discrete Typing Units in Triatoma brasiliensis (Hemiptera: Reduviidae: Triatominae) by Jéssica T. Jales, Lavínia H. S. Pereira, Leomir A. S. de Lima, Raniery de O. Santana, Anne B. F. Câmara, Pedro Ramon da S. Aquino, Paulo Marcos M. Guedes, Andressa Noronha Barbosa-Silva Carvalho, Kássio M. G. Lima, Renata A. Gama, Antonia C. J. Câmara (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12756755.txt.
Description
Jéssica Jales and co-authors read a parasite's strain from a bug's body using light in a 2025 study. Chagas disease surveillance needs to know not just whether a triatomine bug carries Trypanosoma cruzi, but which genetic lineage, since lineages differ in behavior. Standard genotyping means culturing the parasite first, slow work that the field can rarely afford.
Infrared spectroscopy offers a shortcut: shine light on the insect's abdomen and let chemometric models read the spectral fingerprint, no dissection or culture. Bugs were infected with three lineages and a mixture, then scanned over a month. For one lineage, the mixture, and clean controls, the models scored perfect sensitivity and specificity at every time point. A second lineage read best at fifteen days. The authors pitch spectroscopy as a rapid, nondestructive screen that surveillance programs could run at scale.
Catalog record
| CREATOR | Jéssica T. Jales, Lavínia H. S. Pereira, Leomir A. S. de Lima, Raniery de O. Santana, Anne B. F. Câmara, Pedro Ramon da S. Aquino, Paulo Marcos M. Guedes, Andressa Noronha Barbosa-Silva Carvalho, Kássio M. G. Lima, Renata A. Gama, Antonia C. J. Câmara |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |