Analysis of anticancer drug associated adverse reactions in depressive patients from vigibase
Basile Chretien, Charles Dolladille, Kazuki Nishida, Branko Aleksic, Joachim Alexandre, Jean-Matthieu L’orphelin · 2025
Read Analysis of anticancer drug associated adverse reactions in depressive patients from vigibase by Basile Chretien, Charles Dolladille, Kazuki Nishida, Branko Aleksic, Joachim Alexandre, Jean-Matthieu L’orphelin (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12756327.txt.
Description
Chretien and five co-authors mine the world's largest side-effect database for cancer patients with depression, in this two thousand twenty-five study. Depression is common in oncology and may color how patients experience and report drug side effects.
From nearly nine million reports in VigiBase spanning nineteen sixty-eight to two thousand twenty-four, about four hundred twenty-eight thousand involved patients on antidepressants. Those patients' reports were far more likely to describe serious reactions, and reports of fatigue, pain, and headache were all markedly higher. When the antidepressant was started made little difference. The authors urge clinicians to watch this group closely, since treating depression well may ease side-effect burden and help patients stay on therapy.
Catalog record
| CREATOR | Basile Chretien, Charles Dolladille, Kazuki Nishida, Branko Aleksic, Joachim Alexandre, Jean-Matthieu L’orphelin |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |