Drug-related hepatotoxicity risk in elderly patients with atrial fibrillation: insights from the nationwide Italian START registry
Gianluca Gazzaniga, Danilo Menichelli, Daniela Poli, Gualtiero Palareti, Emilia Antonucci, Arianna Pani, Pasquale Pignatelli, Daniele Pastori, Benilde Cosmi, Benilde Cosmi, Daniela Poli, Elena Lotti, Martina Berteotti, Rossella Marcucci, Walter Ageno, Giovanna Colombo, Doris Barcellona, Giovanni Bar · 2025
Read Drug-related hepatotoxicity risk in elderly patients with atrial fibrillation: insights from the nationwide Italian START registry by Gianluca Gazzaniga, Danilo Menichelli, Daniela Poli, Gualtiero Palareti, Emilia Antonucci, Arianna Pani, Pasquale Pignatelli, Daniele Pastori, Benilde Cosmi, Benilde Cosmi, Daniela Poli, Elena Lotti, Martina Berteotti, Rossella Marcucci, Walter Ageno, Giovanna Colombo, Doris Barcellona, Giovanni Bar (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12756272.txt.
Description
Gianluca Gazzaniga and co-authors examine liver risk from medicines in 2025 among older Italians with atrial fibrillation. Such patients take many drugs at once, which raises the chance of liver injury. Using a national registry, the team sorts each patient's drugs by a standard liver-risk list.
The group covered 8,215 patients with a median age of eighty-one, taking a median of five drugs each. Over forty percent took at least one high-risk drug, most often statins, a heart rhythm drug, or a gout drug. Two high-risk drugs linked clearly to abnormal liver tests, as did several common drugs like warfarin. The authors urge liver checks when these drugs combine.
Catalog record
| CREATOR | Gianluca Gazzaniga, Danilo Menichelli, Daniela Poli, Gualtiero Palareti, Emilia Antonucci, Arianna Pani, Pasquale Pignatelli, Daniele Pastori, Benilde Cosmi, Benilde Cosmi, Daniela Poli, Elena Lotti, Martina Berteotti, Rossella Marcucci, Walter Ageno, Giovanna Colombo, Doris Barcellona, Giovanni Bar |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |