Kinematic correlates of early speech motor changes in cognitively intact APOE-ε4 carriers: a preliminary study using a color-word interference task
Mehrdad Dadgostar, Lindsay C. Hanford, Jordan R. Green, Brian D. Richburg, Averi Taylor Cannon, Nelson V. Barnett, David H. Salat, Steven E. Arnold, Marziye Eshghi · 2025
Read Kinematic correlates of early speech motor changes in cognitively intact APOE-ε4 carriers: a preliminary study using a color-word interference task by Mehrdad Dadgostar, Lindsay C. Hanford, Jordan R. Green, Brian D. Richburg, Averi Taylor Cannon, Nelson V. Barnett, David H. Salat, Steven E. Arnold, Marziye Eshghi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12755850.txt.
Description
Nine authors present an early study from two thousand twenty-five on speech movement as a warning sign for Alzheimer's disease. A gene form called APOE-e4 raises the risk of the disease. The authors ask whether fine changes in speech motion show up in healthy carriers of the gene before any thinking problems appear.
Sixteen older adults with normal cognition took part, nine of them gene carriers. They read sentences in a color-word task that pits a word against its ink color. A tracking device recorded lower-lip movement in three dimensions. The team compared movement patterns between carriers and non-carriers, hunting for early motor marks of risk.
Catalog record
| CREATOR | Mehrdad Dadgostar, Lindsay C. Hanford, Jordan R. Green, Brian D. Richburg, Averi Taylor Cannon, Nelson V. Barnett, David H. Salat, Steven E. Arnold, Marziye Eshghi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |