What Factors Contribute to the Poor Prognosis of Conservative Treatment for Osteoporotic Vertebral Compression Fracture (OVCF): A Systematic Review
Jintao Ao, Zhongning Xu, Zhizezhang Gao, Tenghui Ge, Jingye Wu, Jianing Li, Guanqing Li, Qingyun Li, Ronghui Cai, Yuqing Sun · 2025
Read What Factors Contribute to the Poor Prognosis of Conservative Treatment for Osteoporotic Vertebral Compression Fracture (OVCF): A Systematic Review by Jintao Ao, Zhongning Xu, Zhizezhang Gao, Tenghui Ge, Jingye Wu, Jianing Li, Guanqing Li, Qingyun Li, Ronghui Cai, Yuqing Sun (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12755102.txt.
Description
Jintao Ao and nine co-authors present a 2025 systematic review on which spinal fracture patients fare badly when treated without surgery. Osteoporotic vertebral fractures are common in older adults and often managed conservatively, but some patients end with lasting pain, collapse, or deformity. The review gathered twenty-six studies with over four thousand patients, mostly women around seventy-three, all treated conservatively and followed for at least three months.
Age, a previous spine fracture, and steroid use predicted poor outcomes. On plain X-rays, fractures at the thoracolumbar junction, instability, middle-column injury, and certain shapes spelled trouble. MRI added warning signs: particular signal patterns and fatty wasting of the back muscles. The authors say all three lenses, clinical, X-ray, and MRI, can flag risk at first diagnosis. Early flagging lets doctors choose surgery or closer watching before decline sets in.
Catalog record
| CREATOR | Jintao Ao, Zhongning Xu, Zhizezhang Gao, Tenghui Ge, Jingye Wu, Jianing Li, Guanqing Li, Qingyun Li, Ronghui Cai, Yuqing Sun |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 74 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |