Immunological Antagonism Between Psoriasis and Atopic Dermatitis: Pathways, Clinical Implications, and Therapeutic Perspectives

Jiuyuan Qin, Zudong Meng, Wenrui Min, Xinxin Wang, Yulin Zou · 2025

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Description

Jiuyuan Qin and co-authors review the odd rivalry between psoriasis and eczema in a 2025 paper. Both skin diseases now have strong targeted biologic drugs. Sometimes treating one makes the other appear, a paradoxical reaction. Why that flip happens is largely unclear.

The review gathers every reported paradoxical case to date. It folds in fresh gene sequencing studies of both diseases. Opposite immune pathways drive the two conditions, which explains the seesaw. Long-term biologic use raises new watch points for skin doctors. The synthesis helps clinicians pick and switch drugs with care.

Catalog record

CREATORJiuyuan Qin, Zudong Meng, Wenrui Min, Xinxin Wang, Yulin Zou
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12755094

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