Physical activity, sedentary behavior and risk of inflammatory bowel disease: a prospective cohort study in the UK Biobank
Siqin Xia, Jie Zhang, Zixing Zhang, Xiang Wang, Dongqing Ye, Xinyu Fang · 2025
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Description
Xia and co-authors follow a huge British cohort in a 2025 study of bowel disease risk. Movement may calm chronic swelling, while long sitting may upset gut microbes, and both paths feed into inflammatory bowel disease. Past data on the pair of habits stayed mixed. The team tracked 355,021 UK Biobank members who began free of the disease, scoring activity and sitting time by survey.
Over 13.6 years of follow up, 2,242 new cases appeared, split between Crohn's disease and ulcerative colitis. Moderate activity came with about a fifth lower risk than low activity, and high activity also helped. The study weighs sitting and moving apart and together, using models that allow curved dose patterns. Its scale gives doctors firmer ground for lifestyle advice aimed at gut health.
Catalog record
| CREATOR | Siqin Xia, Jie Zhang, Zixing Zhang, Xiang Wang, Dongqing Ye, Xinyu Fang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |