Consistency of primary outcomes in evidence synthesis researches on drug-eluting stents for coronary artery disease

Xiaoqing Lin, Songsong Tan, Yuezi Huang, Jiaojiao Zhao, Jiankun Yao, Die Han, Renlan Luo, Huan Wu, Shuimei Sun, Junjie Lan, Rui Zhang, Huaye Zhao, Linfang Hu, Jiaxue Wang, Wenyi Zheng, Rui He, Jiaxing Zhang · 2025

Read Consistency of primary outcomes in evidence synthesis researches on drug-eluting stents for coronary artery disease by Xiaoqing Lin, Songsong Tan, Yuezi Huang, Jiaojiao Zhao, Jiankun Yao, Die Han, Renlan Luo, Huan Wu, Shuimei Sun, Junjie Lan, Rui Zhang, Huaye Zhao, Linfang Hu, Jiaxue Wang, Wenyi Zheng, Rui He, Jiaxing Zhang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12754870.txt.

Description

Xiaoqing Lin and co-authors audit how stent reviews pick their main outcome in a 2025 study. Systematic reviews of drug-eluting stents keep multiplying. If each names a different primary outcome, or none, the literature cannot be compared or combined fairly.

The team gathered 271 reviews and meta-analyses from English and Chinese databases up to May 2025. Only about sixty-nine percent stated a primary outcome clearly. Having a registered plan in advance tied strongly to stating one. For common outcomes, the audit measured how often each was crowned primary. An overlap index mapped how much the stated outcomes coincide. The paper pushes core outcome sets as the fix.

Catalog record

CREATORXiaoqing Lin, Songsong Tan, Yuezi Huang, Jiaojiao Zhao, Jiankun Yao, Die Han, Renlan Luo, Huan Wu, Shuimei Sun, Junjie Lan, Rui Zhang, Huaye Zhao, Linfang Hu, Jiaxue Wang, Wenyi Zheng, Rui He, Jiaxing Zhang
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12754870

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