Phage therapy of perinephric abscess in kidney transplantation recipients caused by drug‐resistant Pseudomonas aeruginosa

Jiazhen Liu, Shuguang Lu, Juan Bao, Jing Wang, Yali Gong, Bo He, Yuhao Zhu, Zhuojun Zhong, Shiru Li, Linlin Li, Na Li, Mengjun Cheng, Ming Li, Mengyu Shen, Nannan Wu, Tongyu Zhu, Shuai Le · 2025

Read Phage therapy of perinephric abscess in kidney transplantation recipients caused by drug‐resistant Pseudomonas aeruginosa by Jiazhen Liu, Shuguang Lu, Juan Bao, Jing Wang, Yali Gong, Bo He, Yuhao Zhu, Zhuojun Zhong, Shiru Li, Linlin Li, Na Li, Mengjun Cheng, Ming Li, Mengyu Shen, Nannan Wu, Tongyu Zhu, Shuai Le (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12754627.txt.

Description

Jiazhen Liu and co-authors treat two kidney transplant patients whose deep abscesses resisted antibiotics, using viruses that infect bacteria, in a 2025 report. Abscesses beside the transplanted kidney are a known hazard, often driven by drug-resistant Pseudomonas aeruginosa. Phage therapy, matching a patient's bacteria with a virus that kills it, offers an alternative when drugs fail.

Both cases received tailored phage treatment, and the authors draw lessons on timing and personalization from their course. Biofilms, the slime shields bacteria build, remain a barrier the field must beat. The team frame the cases as a step toward routine phage use for transplant patients facing superbugs, with the promise of better survival and quality of life when antibiotics run out.

Catalog record

CREATORJiazhen Liu, Shuguang Lu, Juan Bao, Jing Wang, Yali Gong, Bo He, Yuhao Zhu, Zhuojun Zhong, Shiru Li, Linlin Li, Na Li, Mengjun Cheng, Ming Li, Mengyu Shen, Nannan Wu, Tongyu Zhu, Shuai Le
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE24 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12754627

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