Regional abnormalities in the hippocampus and verbal memory impairment in craniofacial dystonia
Gang Liu, Huiming Liu, Linchang Zhong, Yuhan Luo, Zhengkun Yang, Jiana Zhang, Xiuye He, Zilin Ou, Weixi Zhang, Kangqiang Peng, Jinping Xu, Zhicong Yan, Yue Zhang · 2025
Read Regional abnormalities in the hippocampus and verbal memory impairment in craniofacial dystonia by Gang Liu, Huiming Liu, Linchang Zhong, Yuhan Luo, Zhengkun Yang, Jiana Zhang, Xiuye He, Zilin Ou, Weixi Zhang, Kangqiang Peng, Jinping Xu, Zhicong Yan, Yue Zhang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12753948.txt.
Description
Gang Liu and co-authors ask, in a 2025 study, whether verbal memory problems in a face and neck movement disorder trace to shrinkage in parts of the hippocampus, the brain's memory hub. Patients with craniofacial dystonia often show such memory deficits. Their anatomical basis has been unclear, since the disorder is usually framed as a movement problem.
The team recruited 50 patients with the disorder, 48 with a related face spasm condition, and 50 healthy controls. All took a spoken word learning test for verbal memory, and a brief exam for general cognition. High resolution brain scans were processed to measure hippocampal subfield volumes. General cognition did not differ across the groups. The dystonia group did show weaker verbal memory. Comparing with the spasm group helps isolate what belongs to dystonia itself, rather than to facial symptoms in general.
Catalog record
| CREATOR | Gang Liu, Huiming Liu, Linchang Zhong, Yuhan Luo, Zhengkun Yang, Jiana Zhang, Xiuye He, Zilin Ou, Weixi Zhang, Kangqiang Peng, Jinping Xu, Zhicong Yan, Yue Zhang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |