Targeting gut microbiota with short-chain fructo-oligosaccharides prebiotic fibers to support metabolic health in overweight prediabetic adults: a randomized, double-blinded, placebo-controlled study
Cindy Le Bourgot, Odile Capronnier, Sahara Graf, Thomas Carton · 2025
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Description
Cindy Le Bourgot, Odile Capronnier, Sahara Graf, and Thomas Carton test a prebiotic fiber in overweight adults with prediabetes in a 2025 trial. Sixty six volunteers took either twenty grams a day of short chain fructo-oligosaccharides or a placebo for twelve weeks, in a double blind design. The main target was change in a long term blood sugar marker, with body composition and gut bacteria also tracked.
The sugar marker did not budge significantly, and neither did other glucose measures. Body composition, though, favored the fiber group: fat mass dipped while lean mass rose slightly, both significantly against placebo. Compliance was excellent. The authors present the fiber as a possible body composition aid, not a glucose treatment.
Catalog record
| CREATOR | Cindy Le Bourgot, Odile Capronnier, Sahara Graf, Thomas Carton |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |