Female hormone therapy and risk of intracranial hemorrhage and focal neurological deficits in patients with cavernous malformations of the central nervous system

Saskia Wildi, Selina Nager, Victor Staartjes, Vittorio Stumpo, Sena Özkaratufan, Niklaus Krayenbühl, Oliver Bozinov, Luca Regli, Julia Velz · 2025

Read Female hormone therapy and risk of intracranial hemorrhage and focal neurological deficits in patients with cavernous malformations of the central nervous system by Saskia Wildi, Selina Nager, Victor Staartjes, Vittorio Stumpo, Sena Özkaratufan, Niklaus Krayenbühl, Oliver Bozinov, Luca Regli, Julia Velz (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12753367.txt.

Description

Saskia Wildi and eight co-authors weigh the safety of hormone therapy for women who have cavernous malformations in the brain or spine. These tangles of blood vessels can bleed into the brain, causing stroke or nerve damage. Birth control and menopause hormone treatment are not withheld from such patients, yet proof of their safety here is thin. Their 2025 study searched a hospital's prospective records for all such patients. It compared bleeding and new nerve deficits between those on hormone therapy and those not.

A clear risk number would help women and doctors make a hard trade-off with open eyes. Hormones help many patients, so a blanket ban has costs too. The authors aim to replace guesswork with rates drawn from real follow-up. The study adds to a small pool of data on this group.

Catalog record

CREATORSaskia Wildi, Selina Nager, Victor Staartjes, Vittorio Stumpo, Sena Özkaratufan, Niklaus Krayenbühl, Oliver Bozinov, Luca Regli, Julia Velz
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE22 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12753367

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