Femtosecond Laser Engraving Promotes the Repopulation of Decellularized Human Articular Cartilage
Conny Schneider, Johann Zehetner, Barbara Schädl, Matthias Domke, Claudia Keibl, Bernhard Rieder, Patrick Heimel, Anne Kleiner, Andreas Teuschl-Woller, Susanne Wolbank, Heinz Redl, Sylvia Nürnberger · 2025
Read Femtosecond Laser Engraving Promotes the Repopulation of Decellularized Human Articular Cartilage by Conny Schneider, Johann Zehetner, Barbara Schädl, Matthias Domke, Claudia Keibl, Bernhard Rieder, Patrick Heimel, Anne Kleiner, Andreas Teuschl-Woller, Susanne Wolbank, Heinz Redl, Sylvia Nürnberger (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12753096.txt.
Description
Conny Schneider and eleven co-authors use an ultrafast laser to carve migration paths into donor cartilage for repairing joint defects, in a two thousand twenty-five tissue-building paper. Decellularized human cartilage is the most natural filler, but its dense matrix blocks cells trying to enter.
A femtosecond laser engraved deep, fine patterns without the heat damage of other lasers and even helped strip cells out. The scaffold that resulted stayed far stiffer than common cartilage biomaterials, close to real tissue. Seeded cells colonized the incisions and formed repair tissue resembling hyaline cartilage in makeup and collagen orientation. Tests in a plug model and in mice showed the plugs joined well, hinting fewer long-term graft failures.
Catalog record
| CREATOR | Conny Schneider, Johann Zehetner, Barbara Schädl, Matthias Domke, Claudia Keibl, Bernhard Rieder, Patrick Heimel, Anne Kleiner, Andreas Teuschl-Woller, Susanne Wolbank, Heinz Redl, Sylvia Nürnberger |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |