Heparin‐Induced Thrombocytopenia and Thrombosis in Patients With or Without a Thrombophilia Background: A Systematic Review Involved 602 Cases

Guangyu Han, Siying Song, Shuling Wan, Mengqi Wang, Da Zhou, Xunming Ji, Ran Meng, Peng Geng · 2025

Read Heparin‐Induced Thrombocytopenia and Thrombosis in Patients With or Without a Thrombophilia Background: A Systematic Review Involved 602 Cases by Guangyu Han, Siying Song, Shuling Wan, Mengqi Wang, Da Zhou, Xunming Ji, Ran Meng, Peng Geng (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12752825.txt.

Description

Guangyu Han and co-authors review, in a 2025 paper, 602 cases of a dangerous reaction to the blood thinner heparin, asking whether an inherited clotting tendency changes its course. The reaction drops platelets while paradoxically causing clots, and it strikes about nine days after heparin starts.

Cases came from 481 papers found in two databases. Patients with a prior clotting tendency lost platelets more deeply and formed new vein clots more often than those without. Platelets typically recovered five days after stopping heparin. The comparison supports tailoring treatment to a patient's clotting background rather than one routine for all.

Catalog record

CREATORGuangyu Han, Siying Song, Shuling Wan, Mengqi Wang, Da Zhou, Xunming Ji, Ran Meng, Peng Geng
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE47 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12752825

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