Noninvasive Assessment of Prehepatic Portal Hypertension: Pilot Data on Spleen Stiffness in Portal Vein Thrombosis
Kelly Tin Long Chan, Oi Ling Chan, Yin Yee Lam, Siu Wing Lawrence Lai · 2025
Read Noninvasive Assessment of Prehepatic Portal Hypertension: Pilot Data on Spleen Stiffness in Portal Vein Thrombosis by Kelly Tin Long Chan, Oi Ling Chan, Yin Yee Lam, Siu Wing Lawrence Lai (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12752816.txt.
Description
Kelly Chan and co-authors run a pilot study from 2025 on a scan-free way to judge high pressure in the portal vein when that vein is blocked by a clot. The blockage, portal vein thrombosis, raises pressure before blood reaches the liver. Doctors now track the clot with CT scans and check for harm with a scope passed into the gut.
The team tests spleen stiffness, measured without cutting the skin, as a possible stand-in marker. Spleen stiffness already shows promise for finding serious portal pressure in liver scarring, but its link to clot-based pressure was unknown. Their cross-sectional study at two Hong Kong hospitals ran from early 2023 to spring 2024. It checks whether stiffness tracks the presence of a clot and the problems that high pressure brings.
Catalog record
| CREATOR | Kelly Tin Long Chan, Oi Ling Chan, Yin Yee Lam, Siu Wing Lawrence Lai |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |