A primary neuron culture system for functional studies of anoxia tolerance in turtles
Natalia A Schneider, Claire L Riggs, Mia Warmka, Seth Hofheins, Colton Smith, Daniel E Warren · 2025
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Description
Natalia Schneider and co-authors describe a 2025 lab method for turtle brain cells. Painted turtles stand out for living with no oxygen for long spans. Few lab models exist for brain cells from non-mammal animals. The team built a way to grow cortex cells from young turtles and test them in a dish.
Brain sheets were split into single cells and grown for up to a week. Most cells soon showed classic nerve cell shape, with a body and fine threads. Stain tests showed most cells were nerve cells. The cells fired in response to salt and a brain signal chemical, but not to one other chemical. When oxygen was cut, the cells avoided a harmful burst of reactive oxygen. The system gives labs a new tool to study how turtle brains survive without oxygen.
Catalog record
| CREATOR | Natalia A Schneider, Claire L Riggs, Mia Warmka, Seth Hofheins, Colton Smith, Daniel E Warren |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |